| Unprotected sex (vaginal or anal) | Yes | Possible but less common. Risk is increased if co-infected with sexually transmitted infection/s or HIV | Yes |
| Unprotected oral sex | Yes | Extremely low risk | Extremely low risk |
| Sharing injecting drug equipment | Yes | Yes | Yes |
| Pregnancy, delivery, breastfeeding | Yes – risk can be reduced by screening and immunisation of babies born to infected mothers | Yes | Yes - risks can be reduced by screening and interventions such as treatment and caesarean section |
| Needlestick injury | Yes | Yes | Yes |
| Blood transfusion in UK | Not since 1984 | Not since September 1991 | Not since 1985 |
| Bites/ scratches | Possible if it breaks the skin | No | No |
| Sharing razors, toothbrushes that are contaminated with blood | Low to medium risk | Medium to low risk | Rare |
| Using unsterile equipment for medical, dental, tattooing or piercing procedures | Possible | Possible | Possible |
| Social contact | No | No | No |